Bioactivity | [Des-Arg9]-Bradykinin is a Bradykinin (B1) receptor agonist that displays selectivity for B1 over B2 receptors. |
Invitro | The B2 receptor mediates the action of bradykinin (BK) and lysyl-bradykinin (Lys-BK), the first set of bioactive kinins formed in response to injury from kininogen precursors through the actions of plasma and tissue kallikreins, whereas the B1 receptor mediates the action of [Des-Arg9]-Bradykinin (des-Arg9-BK) and Lys-des-Arg Arg9-BK, the second set of bioactive kinins formed through the actions of carboxypeptidases on BK and Lys-BK, respectively[1]. |
Name | [Des-Arg9]-Bradykinin |
CAS | 15958-92-6 |
Sequence | Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe |
Shortening | RPPGFSPF |
Formula | C44H61N11O10 |
Molar Mass | 904.02 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |